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People with the disease often have high body temperatures. They suffer what are called night sweats, during which their bodies release large amounts of water through the skin. TB victims also are tired all the time. They are not interested in eating. So their bodies lose weight.
Experts say TB is a preventable disease. The goal of health organizations is to quickly identify infected persons – especially those who have the highest risk of developing the disease. There are several drugs that can prevent tuberculosis in these people.
This SCIENCE IN THE NEWS was written by George Grow and Shelley Gollust. Brianna Blake was our producer. I'm Barbara Klein.
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There are several ways to test for TB. The first is the TB skin test. It also is known as the Mantoux skin test. The test can identify most people infected with tuberculosis six to eight weeks after the bacteria entered their bodies. A substance called purified protein derivative is injected under the skin of the arm. The place of the injection is examined two to three days later.
If this continues for the next three or four years, WHO officials believe their Millennium Development Goal could be reached. The goal is to discover at least seventy percent of TB cases and successfully treat eighty-five percent of those cases by the year two thousand fifteen.
If a person becomes infected with the TB bacteria, it does not mean he or she has the disease. Having the infection means that the bacteria are in the body, but they may be neutral, or inactive.
Tuberculosis can attack any part of the body. However, the lungs are the most common targets of the bacteria. People with the disease show several signs. They may expel air from the lungs suddenly with an explosive noise. This kind of cough continues for a long period of time. People with a more severe case of tuberculosis also may cough up blood.
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If the natural immune system against disease is weak, however, a person can get tuberculosis soon after the TB bacteria enter the body. Also, inactive TB bacteria may become active if the immune system becomes weak. When this happens, the bacteria begin reproducing and damaging the lungs or other organs and causing serious sickness.
If the skin test shows that TB bacteria have entered the body, doctors can use other methods to discover if the person has active TB. However, this sometimes can be difficult because tuberculosis may appear similar to other diseases. Doctors must consider other physical signs. Also, they must decide if a person's history shows that he or she has been in situations where tuberculosis was present.
The World Health Organization has a five-step program to guarantee that TB patients take their medicine correctly. The program is called Directly Observed Treatment, Short-course, or DOTS. Directly observed means that local health care workers watch to make sure patients take their medicine every day. Full treatment usually lasts from six to nine months to destroy all signs of the bacteria.
Tuberculosis is one of the leading infectious diseases. The World Health Organization says two billion people are infected with the TB bacteria. That is about one-third of the world's total population.
The inactive TB bacteria can become active under several conditions. When a person becomes old, the immune system may become too weak to protect against the bacteria. The virus that causes AIDS can cause TB bacteria to become active. Also, doctors warn that people who drink too much alcohol or use drugs have a higher risk of becoming sick from the tuberculosis bacteria.
It is very important for doctors to identify which kind of TB bacteria are present so they can decide which drugs to use to treat the disease. Most TB cases can be successfully treated with medicines. However, the death rate for untreated patients is reported to be about fifty percent. Successful treatment of TB requires close cooperation among patients, doctors and other health care workers.
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One thing that is especially dangerous about TB is that people with moderate signs of the disease may not know they have it. They may spread the disease to others without even knowing it. So, it is very important for people to get tested for tuberculosis.
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